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The Role of Selection in Shaping Diversity of Natural M. tuberculosis Populations

Mycobacterium tuberculosis (M.tb), the cause of tuberculosis (TB), is estimated to infect a new host every second. While analyses of genetic data from natural populations of M.tb have emphasized the role of genetic drift in shaping patterns of diversity, the influence of natural selection on this su...

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Detalles Bibliográficos
Autores principales: Pepperell, Caitlin S., Casto, Amanda M., Kitchen, Andrew, Granka, Julie M., Cornejo, Omar E., Holmes, Eddie C., Birren, Bruce, Galagan, James, Feldman, Marcus W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744410/
https://www.ncbi.nlm.nih.gov/pubmed/23966858
http://dx.doi.org/10.1371/journal.ppat.1003543