Cargando…

Francisella tularensis Harvests Nutrients Derived via ATG5-Independent Autophagy to Support Intracellular Growth

Francisella tularensis is a highly virulent intracellular pathogen that invades and replicates within numerous host cell types including macrophages, hepatocytes and pneumocytes. By 24 hours post invasion, F. tularensis replicates up to 1000-fold in the cytoplasm of infected cells. To achieve such r...

Descripción completa

Detalles Bibliográficos
Autores principales: Steele, Shaun, Brunton, Jason, Ziehr, Benjamin, Taft-Benz, Sharon, Moorman, Nathaniel, Kawula, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744417/
https://www.ncbi.nlm.nih.gov/pubmed/23966861
http://dx.doi.org/10.1371/journal.ppat.1003562