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Francisella tularensis Harvests Nutrients Derived via ATG5-Independent Autophagy to Support Intracellular Growth
Francisella tularensis is a highly virulent intracellular pathogen that invades and replicates within numerous host cell types including macrophages, hepatocytes and pneumocytes. By 24 hours post invasion, F. tularensis replicates up to 1000-fold in the cytoplasm of infected cells. To achieve such r...
Autores principales: | Steele, Shaun, Brunton, Jason, Ziehr, Benjamin, Taft-Benz, Sharon, Moorman, Nathaniel, Kawula, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744417/ https://www.ncbi.nlm.nih.gov/pubmed/23966861 http://dx.doi.org/10.1371/journal.ppat.1003562 |
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