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Metabonomics Reveals Drastic Changes in Anti-Inflammatory/Pro-Resolving Polyunsaturated Fatty Acids-Derived Lipid Mediators in Leprosy Disease

Despite considerable efforts over the last decades, our understanding of leprosy pathogenesis remains limited. The complex interplay between pathogens and hosts has profound effects on host metabolism. To explore the metabolic perturbations associated with leprosy, we analyzed the serum metabolome o...

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Detalles Bibliográficos
Autores principales: Amaral, Julio J., Antunes, Luis Caetano M., de Macedo, Cristiana S., Mattos, Katherine A., Han, Jun, Pan, Jingxi, Candéa, André L. P., Henriques, Maria das Graças M. O., Ribeiro-Alves, Marcelo, Borchers, Christoph H., Sarno, Euzenir N., Bozza, Patrícia T., Finlay, B. Brett, Pessolani, Maria Cristina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744420/
https://www.ncbi.nlm.nih.gov/pubmed/23967366
http://dx.doi.org/10.1371/journal.pntd.0002381