A Flexible Approach for the Analysis of Rare Variants Allowing for a Mixture of Effects on Binary or Quantitative Traits

Multiple rare variants either within or across genes have been hypothesised to collectively influence complex human traits. The increasing availability of high throughput sequencing technologies offers the opportunity to study the effect of rare variants on these traits. However, appropriate and com...

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Detalles Bibliográficos
Autores principales: Clarke, Geraldine M., Rivas, Manuel A., Morris, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744430/
https://www.ncbi.nlm.nih.gov/pubmed/23966874
http://dx.doi.org/10.1371/journal.pgen.1003694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744430/
https://www.ncbi.nlm.nih.gov/pubmed/23966874
http://dx.doi.org/10.1371/journal.pgen.1003694

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