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The Malnutrition-Related Increase in Early Visceralization of Leishmania donovani Is Associated with a Reduced Number of Lymph Node Phagocytes and Altered Conduit System Flow

In a murine model of moderate childhood malnutrition we found that polynutrient deficiency led to a 4–5-fold increase in early visceralization of L. donovani (3 days post-infection) following cutaneous infection and a 16-fold decrease in lymph node barrier function (p<0.04 for all). To begin to u...

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Detalles Bibliográficos
Autores principales: Ibrahim, Marwa K., Barnes, Jeffrey L., Anstead, Gregory M., Jimenez, Fabio, Travi, Bruno L., Peniche, Alex G., Osorio, E. Yaneth, Ahuja, Seema S., Melby, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744437/
https://www.ncbi.nlm.nih.gov/pubmed/23967356
http://dx.doi.org/10.1371/journal.pntd.0002329