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Subunit Vaccine Consisting of Multi-Stage Antigens Has High Protective Efficacy against Mycobacterium tuberculosis Infection in Mice

To search for more effective tuberculosis (TB) subunit vaccines, antigens expressed in different growth stages of Mycobacterium tuberculosis (M. tuberculosis), such as RpfE (Rv2450c) produced in the stage of resuscitation, Mtb10.4 (Rv0288), Mtb8.4 (Rv1174c), ESAT6 (Rv3875), Ag85B (Rv1886c) mainly se...

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Detalles Bibliográficos
Autores principales: Xin, Qi, Niu, Hongxia, Li, Zhi, Zhang, Guoping, Hu, Lina, Wang, Bingxiang, Li, Jingjing, Yu, Hongjuan, Liu, Wanbo, Wang, Yue, Da, Zejiao, Li, Ruiying, Xian, Qiaoyang, Wang, Yong, Zhang, Ying, Jing, Tao, Ma, Xingming, Zhu, Bingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744459/
https://www.ncbi.nlm.nih.gov/pubmed/23967337
http://dx.doi.org/10.1371/journal.pone.0072745