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Mitochondria Are the Target Organelle of Differentiation-Inducing Factor-3, an Anti-Tumor Agent Isolated from Dictyostelium Discoideum

Differentiation-inducing factor-3 (DIF-3), found in the cellular slime mold Dictyostelium discoideum, and its derivatives such as butoxy-DIF-3 (Bu-DIF-3) are potent anti-tumor agents. However, the precise mechanisms underlying the actions of DIF-3 remain to be elucidated. In this study, we synthesiz...

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Detalles Bibliográficos
Autores principales: Kubohara, Yuzuru, Kikuchi, Haruhisa, Matsuo, Yusuke, Oshima, Yoshiteru, Homma, Yoshimi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744471/
https://www.ncbi.nlm.nih.gov/pubmed/23977224
http://dx.doi.org/10.1371/journal.pone.0072118