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Octyl Gallate Markedly Promotes Anti-Amyloidogenic Processing of APP through Estrogen Receptor-Mediated ADAM10 Activation

Our previous studies showed that the green tea-derived polyphenolic compound (−)-epigallocatechin-3 gallate (EGCG) reduces amyloid-β (Aβ) production in both neuronal and mouse Alzheimer’s disease (AD) models in concert with activation of estrogen receptor-α/phosphatidylinositide 3-kinase/protein kin...

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Detalles Bibliográficos
Autores principales: Zhang, She-Qing, Sawmiller, Darrell, Li, Song, Rezai-Zadeh, Kavon, Hou, Huayan, Zhou, Shufeng, Shytle, Douglas, Giunta, Brian, Fernandez, Frank, Mori, Takashi, Tan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744472/
https://www.ncbi.nlm.nih.gov/pubmed/23977176
http://dx.doi.org/10.1371/journal.pone.0071913