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Octyl Gallate Markedly Promotes Anti-Amyloidogenic Processing of APP through Estrogen Receptor-Mediated ADAM10 Activation
Our previous studies showed that the green tea-derived polyphenolic compound (−)-epigallocatechin-3 gallate (EGCG) reduces amyloid-β (Aβ) production in both neuronal and mouse Alzheimer’s disease (AD) models in concert with activation of estrogen receptor-α/phosphatidylinositide 3-kinase/protein kin...
Autores principales: | Zhang, She-Qing, Sawmiller, Darrell, Li, Song, Rezai-Zadeh, Kavon, Hou, Huayan, Zhou, Shufeng, Shytle, Douglas, Giunta, Brian, Fernandez, Frank, Mori, Takashi, Tan, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744472/ https://www.ncbi.nlm.nih.gov/pubmed/23977176 http://dx.doi.org/10.1371/journal.pone.0071913 |
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