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Targeted Mutagenesis in the Malaria Mosquito Using TALE Nucleases
Anopheles gambiae, the main mosquito vector of human malaria, is a challenging organism to manipulate genetically. As a consequence, reverse genetics studies in this disease vector have been largely limited to RNA interference experiments. Here, we report the targeted disruption of the immunity gene...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744473/ https://www.ncbi.nlm.nih.gov/pubmed/23977401 http://dx.doi.org/10.1371/journal.pone.0074511 |