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Implication of IRF4 Aberrant Gene Expression in the Acute Leukemias of Childhood

The most frequent targets of genetic alterations in human leukemias are transcription factor genes with essential functions in normal blood cell development. The Interferon Regulatory Factor 4 (IRF4) gene encodes a transcription factor important for key developmental stages of hematopoiesis, with kn...

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Detalles Bibliográficos
Autores principales: Adamaki, Maria, Lambrou, George I., Athanasiadou, Anastasia, Tzanoudaki, Marianna, Vlahopoulos, Spiros, Moschovi, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744475/
https://www.ncbi.nlm.nih.gov/pubmed/23977280
http://dx.doi.org/10.1371/journal.pone.0072326