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Implication of IRF4 Aberrant Gene Expression in the Acute Leukemias of Childhood
The most frequent targets of genetic alterations in human leukemias are transcription factor genes with essential functions in normal blood cell development. The Interferon Regulatory Factor 4 (IRF4) gene encodes a transcription factor important for key developmental stages of hematopoiesis, with kn...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744475/ https://www.ncbi.nlm.nih.gov/pubmed/23977280 http://dx.doi.org/10.1371/journal.pone.0072326 |