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Matrix Metalloproteinase-9 Inhibition Improves Proliferation and Engraftment of Myogenic Cells in Dystrophic Muscle of mdx Mice

Duchenne muscular dystrophy (DMD) caused by loss of cytoskeletal protein dystrophin is a devastating disorder of skeletal muscle. Primary deficiency of dystrophin leads to several secondary pathological changes including fiber degeneration and regeneration, extracellular matrix breakdown, inflammati...

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Detalles Bibliográficos
Autores principales: Hindi, Sajedah M., Shin, Jonghyun, Ogura, Yuji, Li, Hong, Kumar, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744489/
https://www.ncbi.nlm.nih.gov/pubmed/23977226
http://dx.doi.org/10.1371/journal.pone.0072121