Carboxypeptidase E/NFα1: A New Neurotrophic Factor against Oxidative Stress-Induced Apoptotic Cell Death Mediated by ERK and PI3-K/AKT Pathways

Mice lacking Carboxypeptidase E (CPE) exhibit degeneration of hippocampal neurons caused by stress at weaning while over-expression of CPE in hippocampal neurons protect them against hydrogen peroxide-induced cell death. Here we demonstrate that CPE acts as an extracellular trophic factor to protect...

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Detalles Bibliográficos
Autores principales: Cheng, Yong, Cawley, Niamh X., Loh, Y. Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744492/
https://www.ncbi.nlm.nih.gov/pubmed/23977080
http://dx.doi.org/10.1371/journal.pone.0071578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744492/
https://www.ncbi.nlm.nih.gov/pubmed/23977080
http://dx.doi.org/10.1371/journal.pone.0071578

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