PKC Activation in Niemann Pick C1 Cells Restores Subcellular Cholesterol Transport

Activation of protein kinase C (PKC) has previously been shown to ameliorate the cholesterol transport defect in Niemann Pick Type C1 (NPC1) cells, presumably by increasing the soluble levels of one of its substrates, vimentin. This activity would then restore the vimentin cycle in these cells and a...

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Detalles Bibliográficos
Autores principales: Tamari, Farshad, Chen, Fannie W., Li, Chunlei, Chaudhari, Jagrutiben, Ioannou, Yiannis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744505/
https://www.ncbi.nlm.nih.gov/pubmed/23977398
http://dx.doi.org/10.1371/journal.pone.0074169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744505/
https://www.ncbi.nlm.nih.gov/pubmed/23977398
http://dx.doi.org/10.1371/journal.pone.0074169

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