Intron Retention in mRNA Encoding Ancillary Subunit of Insect Voltage-Gated Sodium Channel Modulates Channel Expression, Gating Regulation and Drug Sensitivity

Insect voltage-gated sodium (Na(v)) channels are formed by a well-known pore-forming α-subunit encoded by para-like gene and ancillary subunits related to TipE from the mutation “temperature-induced-paralysis locus E.” The role of these ancillary subunits in the modulation of biophysical and pharmac...

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Detalles Bibliográficos
Autores principales: Bourdin, Céline M., Moignot, Bénédicte, Wang, Lingxin, Murillo, Laurence, Juchaux, Marjorie, Quinchard, Sophie, Lapied, Bruno, Guérineau, Nathalie C., Dong, Ke, Legros, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744522/
https://www.ncbi.nlm.nih.gov/pubmed/23967047
http://dx.doi.org/10.1371/journal.pone.0067290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744522/
https://www.ncbi.nlm.nih.gov/pubmed/23967047
http://dx.doi.org/10.1371/journal.pone.0067290

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