Grape Seed Procyanidin Reversal of P-glycoprotein Associated Multi-Drug Resistance via Down-regulation of NF-κB and MAPK/ERK Mediated YB-1 Activity in A2780/T Cells

The expression and function of P-glycoprotein (P-gp) is associated with the phenotype of multi-drug resistance (MDR), leading chemotherapy failure of patients suffered with cancer. Grape seed procyanidin(GSP) is a natural polyphenol supplement with anti-inflammatory effect. Present study assessed a...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Bo-xin, Sun, Ya-bin, Wang, Sheng-qi, Duan, Lian, Huo, Qi-lu, Ren, Fei, Li, Guo-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744527/
https://www.ncbi.nlm.nih.gov/pubmed/23967153
http://dx.doi.org/10.1371/journal.pone.0071071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744527/
https://www.ncbi.nlm.nih.gov/pubmed/23967153
http://dx.doi.org/10.1371/journal.pone.0071071

Ejemplares similares