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Grape Seed Procyanidin Reversal of P-glycoprotein Associated Multi-Drug Resistance via Down-regulation of NF-κB and MAPK/ERK Mediated YB-1 Activity in A2780/T Cells

The expression and function of P-glycoprotein (P-gp) is associated with the phenotype of multi-drug resistance (MDR), leading chemotherapy failure of patients suffered with cancer. Grape seed procyanidin(GSP) is a natural polyphenol supplement with anti-inflammatory effect. Present study assessed a...

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Detalles Bibliográficos
Autores principales:	Zhao, Bo-xin, Sun, Ya-bin, Wang, Sheng-qi, Duan, Lian, Huo, Qi-lu, Ren, Fei, Li, Guo-feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744527/ https://www.ncbi.nlm.nih.gov/pubmed/23967153 http://dx.doi.org/10.1371/journal.pone.0071071

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