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Assessment of Hepatic Detoxification Activity: Proposal of an Improved Variant of the (13)C-Methacetin Breath Test
Breath tests based on the administration of a (13)C-labeled drug and subsequent monitoring of (13)CO(2) in the breath (quantified as DOB – delta over baseline) liberated from the drug during hepatic CPY-dependent detoxification are important tools in liver function diagnostics. The capability of suc...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744534/ https://www.ncbi.nlm.nih.gov/pubmed/23967104 http://dx.doi.org/10.1371/journal.pone.0070780 |