Specific Inhibition of the Redox Activity of Ape1/Ref-1 by E3330 Blocks Tnf-Α-Induced Activation of Il-8 Production in Liver Cancer Cell Lines

APE1/Ref-1 is a main regulator of cellular response to oxidative stress via DNA-repair function and co-activating activity on the NF-κB transcription factor. APE1 is central in controlling the oxidative stress-based inflammatory processes through modulation of cytokines expression and its overexpres...

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Detalles Bibliográficos
Autores principales: Cesaratto, Laura, Codarin, Erika, Vascotto, Carlo, Leonardi, Antonio, Kelley, Mark R., Tiribelli, Claudio, Tell, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744539/
https://www.ncbi.nlm.nih.gov/pubmed/23967134
http://dx.doi.org/10.1371/journal.pone.0070909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744539/
https://www.ncbi.nlm.nih.gov/pubmed/23967134
http://dx.doi.org/10.1371/journal.pone.0070909

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