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Cognitive Dysfunction Precedes the Onset of Motor Symptoms in the MitoPark Mouse Model of Parkinson’s Disease

Parkinson’s disease (PD) is a neurodegenerative disorder primarily characterized by progressive loss of dopamine neurons, leading to loss of motor coordination. However, PD is associated with a high rate of non-motor neuropsychiatric comorbities that often develop before the onset of movement sympto...

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Detalles Bibliográficos
Autores principales: Li, Xiuhua, Redus, Laney, Chen, Cang, Martinez, Paul A., Strong, Randy, Li, Senlin, O’Connor, Jason C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744561/
https://www.ncbi.nlm.nih.gov/pubmed/23977020
http://dx.doi.org/10.1371/journal.pone.0071341