Disruption in Connexin-Based Communication Is Associated with Intracellular Ca(2+) Signal Alterations in Astrocytes from Niemann-Pick Type C Mice

Reduced astrocytic gap junctional communication and enhanced hemichannel activity were recently shown to increase astroglial and neuronal vulnerability to neuroinflammation. Moreover, increasing evidence suggests that neuroinflammation plays a pivotal role in the development of Niemann-Pick type C (...

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Detalles Bibliográficos
Autores principales: Sáez, Pablo J., Orellana, Juan A., Vega-Riveros, Natalia, Figueroa, Vania A., Hernández, Diego E., Castro, Juan F., Klein, Andrés D., Jiang, Jean X., Zanlungo, Silvana, Sáez, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744576/
https://www.ncbi.nlm.nih.gov/pubmed/23977027
http://dx.doi.org/10.1371/journal.pone.0071361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744576/
https://www.ncbi.nlm.nih.gov/pubmed/23977027
http://dx.doi.org/10.1371/journal.pone.0071361

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