Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria

Paroxysmal nocturnal haemoglobinuria (PNH) is characterized by chronic, uncontrolled complement activation resulting in elevated intravascular haemolysis and morbidities, including fatigue, dyspnoea, abdominal pain, pulmonary hypertension, thrombotic events (TEs) and chronic kidney disease (CKD). Th...

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Detalles Bibliográficos
Autores principales: Hillmen, Peter, Muus, Petra, Röth, Alexander, Elebute, Modupe O, Risitano, Antonio M, Schrezenmeier, Hubert, Szer, Jeffrey, Browne, Paul, Maciejewski, Jaroslaw P, Schubert, Jörg, Urbano-Ispizua, Alvaro, de Castro, Carlos, Socié, Gérard, Brodsky, Robert A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Haematological Malignancy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744747/
https://www.ncbi.nlm.nih.gov/pubmed/23617322
http://dx.doi.org/10.1111/bjh.12347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744747/
https://www.ncbi.nlm.nih.gov/pubmed/23617322
http://dx.doi.org/10.1111/bjh.12347

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