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Role of PCNA and TLS polymerases in D-loop extension during homologous recombination in humans()
Homologous recombination (HR) is essential for maintaining genomic integrity, which is challenged by a wide variety of potentially lethal DNA lesions. Regardless of the damage type, recombination is known to proceed by RAD51-mediated D-loop formation, followed by DNA repair synthesis. Nevertheless,...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744802/ https://www.ncbi.nlm.nih.gov/pubmed/23731732 http://dx.doi.org/10.1016/j.dnarep.2013.05.001 |