Role of PCNA and TLS polymerases in D-loop extension during homologous recombination in humans()

Homologous recombination (HR) is essential for maintaining genomic integrity, which is challenged by a wide variety of potentially lethal DNA lesions. Regardless of the damage type, recombination is known to proceed by RAD51-mediated D-loop formation, followed by DNA repair synthesis. Nevertheless,...

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Detalles Bibliográficos
Autores principales: Sebesta, Marek, Burkovics, Peter, Juhasz, Szilvia, Zhang, Sufang, Szabo, Judit E., Lee, Marietta Y.W.T., Haracska, Lajos, Krejci, Lumir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744802/
https://www.ncbi.nlm.nih.gov/pubmed/23731732
http://dx.doi.org/10.1016/j.dnarep.2013.05.001

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