Oskar Is Targeted for Degradation by the Sequential Action of Par-1, GSK-3, and the SCF(-Slimb) Ubiquitin Ligase

Translation of oskar messenger RNA (mRNA) is activated at the posterior of the Drosophila oocyte, producing Long Oskar, which anchors the RNA, and Short Oskar, which nucleates the pole plasm, containing the posterior and germline determinants. Here, we show that Oskar is phosphorylated by Par-1 and...

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Detalles Bibliográficos
Autores principales: Morais-de-Sá, Eurico, Vega-Rioja, Antonio, Trovisco, Vítor, St Johnston, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744808/
https://www.ncbi.nlm.nih.gov/pubmed/23948254
http://dx.doi.org/10.1016/j.devcel.2013.06.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744808/
https://www.ncbi.nlm.nih.gov/pubmed/23948254
http://dx.doi.org/10.1016/j.devcel.2013.06.011

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