MATCHCLIP: locate precise breakpoints for copy number variation using CIGAR string by matching soft clipped reads

Copy number variations (CNVs) are associated with many complex diseases. Next generation sequencing data enable one to identify precise CNV breakpoints to better under the underlying molecular mechanisms and to design more efficient assays. Using the CIGAR strings of the reads, we develop a method t...

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Detalles Bibliográficos
Autores principales: Wu, Yinghua, Tian, Lifeng, Pirastu, Mario, Stambolian, Dwight, Li, Hongzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744852/
https://www.ncbi.nlm.nih.gov/pubmed/23967014
http://dx.doi.org/10.3389/fgene.2013.00157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744852/
https://www.ncbi.nlm.nih.gov/pubmed/23967014
http://dx.doi.org/10.3389/fgene.2013.00157

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