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MATCHCLIP: locate precise breakpoints for copy number variation using CIGAR string by matching soft clipped reads
Copy number variations (CNVs) are associated with many complex diseases. Next generation sequencing data enable one to identify precise CNV breakpoints to better under the underlying molecular mechanisms and to design more efficient assays. Using the CIGAR strings of the reads, we develop a method t...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744852/ https://www.ncbi.nlm.nih.gov/pubmed/23967014 http://dx.doi.org/10.3389/fgene.2013.00157 |