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Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15

The AP-5 complex is a recently identified but evolutionarily ancient member of the family of heterotetrameric adaptor proteins (AP complexes). It is associated with two proteins that are mutated in patients with hereditary spastic paraplegia, SPG11 and SPG15. Here we show that the four AP-5 subunits...

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Detalles Bibliográficos
Autores principales: Hirst, Jennifer, Borner, Georg H. H., Edgar, James, Hein, Marco Y., Mann, Matthias, Buchholz, Frank, Antrobus, Robin, Robinson, Margaret S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744948/
https://www.ncbi.nlm.nih.gov/pubmed/23825025
http://dx.doi.org/10.1091/mbc.E13-03-0170