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Normal CFTR Inhibits Epidermal Growth Factor Receptor-Dependent Pro-Inflammatory Chemokine Production in Human Airway Epithelial Cells

Mutations in cystic fibrosis transmembrane conductance regulator (CFTR) protein cause cystic fibrosis, a disease characterized by exaggerated airway epithelial production of the neutrophil chemokine interleukin (IL)-8, which results in exuberant neutrophilic inflammation. Because activation of an ep...

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Detalles Bibliográficos
Autores principales: Kim, Suil, Beyer, Brittney A., Lewis, Courtney, Nadel, Jay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745379/
https://www.ncbi.nlm.nih.gov/pubmed/23977375
http://dx.doi.org/10.1371/journal.pone.0072981