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Development of In Situ Gelling and Bio Adhesive 5-Fluorouracil Enema
In this study, a novel 5-Fluorouracil (5-FU) enema with good bio adhesion and temperature sensitivity was developed using in situ gelling technology. The preparation was formulated as a free-flowing liquid before use, while a layer of gel film was quickly formed when administered in the rectum, with...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745382/ https://www.ncbi.nlm.nih.gov/pubmed/23976976 http://dx.doi.org/10.1371/journal.pone.0071037 |