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Genetic Variation in BCL2 3′-UTR Was Associated with Lung Cancer Risk and Prognosis in Male Chinese Population

OBJECTIVES: Bcl-2 is a critical apoptosis inhibitor with established carcinogenic potential, and can confer cancer cell resistance to therapeutic treatments by activating anti-apoptotic cellular defense. We hypothesized that genetic variants of BCL2 gene may be associated with lung cancer susceptibi...

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Detalles Bibliográficos
Autores principales: Xu, Ping, Liu, Li, Wang, Jianzhong, Zhang, Kai, Hong, Xiaohua, Deng, Qifei, Xiang, Jingjun, Zhang, Xiaomin, He, Meian, Wu, Tangchun, Guo, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745400/
https://www.ncbi.nlm.nih.gov/pubmed/23977251
http://dx.doi.org/10.1371/journal.pone.0072197