Runs of Homozygosity Associated with Speech Delay in Autism in a Taiwanese Han Population: Evidence for the Recessive Model

Runs of homozygosity (ROH) may play a role in complex diseases. In the current study, we aimed to test if ROHs are linked to the risk of autism and related language impairment. We analyzed 546,080 SNPs in 315 Han Chinese affected with autism and 1,115 controls. ROH was defined as an extended homozyg...

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Detalles Bibliográficos
Autores principales: Lin, Ping-I, Kuo, Po-Hsiu, Chen, Chia-Hsiang, Wu, Jer-Yuarn, Gau, Susan S-F., Wu, Yu-Yu, Liu, Shih-Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745408/
https://www.ncbi.nlm.nih.gov/pubmed/23977206
http://dx.doi.org/10.1371/journal.pone.0072056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745408/
https://www.ncbi.nlm.nih.gov/pubmed/23977206
http://dx.doi.org/10.1371/journal.pone.0072056

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