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Lats2 Modulates Adipocyte Proliferation and Differentiation via Hippo Signaling
First identified in Drosophila and highly conserved in mammals, the Hippo pathway controls organ size. Lats2 is one of the core kinases of the Hippo pathway and plays major roles in cell proliferation by interacting with the downstream transcriptional cofactors YAP and TAZ. Although the function of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745423/ https://www.ncbi.nlm.nih.gov/pubmed/23977200 http://dx.doi.org/10.1371/journal.pone.0072042 |