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Computational and Experimental Validation of B and T-Cell Epitopes of the In Vivo Immune Response to a Novel Malarial Antigen

Vaccine development efforts will be guided by algorithms that predict immunogenic epitopes. Such prediction methods rely on classification-based algorithms that are trained against curated data sets of known B and T cell epitopes. It is unclear whether this empirical approach can be applied prospect...

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Detalles Bibliográficos
Autores principales: Bergmann-Leitner, Elke S., Chaudhury, Sidhartha, Steers, Nicholas J., Sabato, Mark, Delvecchio, Vito, Wallqvist, Anders S., Ockenhouse, Christian F., Angov, Evelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745447/
https://www.ncbi.nlm.nih.gov/pubmed/23977087
http://dx.doi.org/10.1371/journal.pone.0071610