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Down-Regulation of the Oncogene PTTG1 via the KLF6 Tumor Suppressor during Induction of Myeloid Differentiation

The aberrant expression of proto-oncogenes is involved in processes that are responsible for cellular proliferation and the inhibition of myeloid differentiation in acute myeloid leukemia (AML). Pituitary Tumor-Transforming gene 1 (PTTG1), an oncogenic transcription factor, is abundantly expressed i...

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Detalles Bibliográficos
Autores principales: Chen, Pei-Yi, Yen, Jui-Hung, Kao, Ruey-Ho, Chen, Ji-Hshiung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745464/
https://www.ncbi.nlm.nih.gov/pubmed/23977008
http://dx.doi.org/10.1371/journal.pone.0071282