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Down-Regulation of the Oncogene PTTG1 via the KLF6 Tumor Suppressor during Induction of Myeloid Differentiation
The aberrant expression of proto-oncogenes is involved in processes that are responsible for cellular proliferation and the inhibition of myeloid differentiation in acute myeloid leukemia (AML). Pituitary Tumor-Transforming gene 1 (PTTG1), an oncogenic transcription factor, is abundantly expressed i...
Autores principales: | Chen, Pei-Yi, Yen, Jui-Hung, Kao, Ruey-Ho, Chen, Ji-Hshiung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745464/ https://www.ncbi.nlm.nih.gov/pubmed/23977008 http://dx.doi.org/10.1371/journal.pone.0071282 |
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