Phospholipids Induce Conformational Changes of SecA to Form Membrane-Specific Domains: AFM Structures and Implication on Protein-Conducting Channels

SecA, an essential component of the Sec machinery, exists in a soluble and a membrane form in Escherichia coli. Previous studies have shown that the soluble SecA transforms into pore structures when it interacts with liposomes, and integrates into membranes containing SecYEG in two forms: SecA(S) an...

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Detalles Bibliográficos
Autores principales: You, Zhipeng, Liao, Meijiang, Zhang, Hao, Yang, Hsiuchin, Pan, Xijian, Houghton, John E., Sui, Sen-fang, Tai, Phang C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745498/
https://www.ncbi.nlm.nih.gov/pubmed/23977317
http://dx.doi.org/10.1371/journal.pone.0072560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745498/
https://www.ncbi.nlm.nih.gov/pubmed/23977317
http://dx.doi.org/10.1371/journal.pone.0072560

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