Rotenone Upregulates Alpha-Synuclein and Myocyte Enhancer Factor 2D Independently from Lysosomal Degradation Inhibition

Dysfunctions of chaperone-mediated autophagy (CMA), the main catabolic pathway for alpha-synuclein, have been linked to the pathogenesis of Parkinson's disease (PD). Since till now there is limited information on how PD-related toxins may affect CMA, in this study we explored the effect of mito...

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Detalles Bibliográficos
Autores principales: Sala, Gessica, Arosio, Alessandro, Stefanoni, Giovanni, Melchionda, Laura, Riva, Chiara, Marinig, Daniele, Brighina, Laura, Ferrarese, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745903/
https://www.ncbi.nlm.nih.gov/pubmed/23984410
http://dx.doi.org/10.1155/2013/846725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745903/
https://www.ncbi.nlm.nih.gov/pubmed/23984410
http://dx.doi.org/10.1155/2013/846725

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