Cargando…

High Glucose-Induced Oxidative Stress Increases the Copy Number of Mitochondrial DNA in Human Mesangial Cells

Oxidative damage to mitochondrial DNA (mtDNA) has been linked to the pathogenicity of diabetic nephropathy. We tested the hypothesis that mtDNA copy number may be increased in human mesangial cells in response to high glucose-induced reactive oxygen species (ROS) to compensate for damaged mtDNA. The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Al-Kafaji, Ghada, Golbahar, Jamal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745925/ https://www.ncbi.nlm.nih.gov/pubmed/23984405 http://dx.doi.org/10.1155/2013/754946

Ejemplares similares

Comprehensive analysis of mitochondrial DNA variants, mitochondrial DNA copy number and oxidative damage in psoriatic arthritis
por: Alwehaidah, Materah Salem, et al.
Publicado: (2023)

Leukocyte mitochondrial DNA copy number is a potential non-invasive biomarker for psoriasis
por: Alwehaidah, Materah Salem, et al.
Publicado: (2022)

Mitochondrial DNA copy number in autism spectrum disorder and attention deficit hyperactivity disorder: a systematic review and meta-analysis
por: Al-Kafaji, Ghada, et al.
Publicado: (2023)

Keratoconus is associated with increased copy number of mitochondrial DNA
por: Abu-Amero, Khaled. K., et al.
Publicado: (2014)

Increased Mitochondrial DNA Copy Number and Oxidative Damage in Patients with Hashimoto’s Thyroiditis
por: Esfahanian, Fatemeh, et al.
Publicado: (2021)

Overexpression of TFAM or Twinkle Increases mtDNA Copy Number and Facilitates Cardioprotection Associated with Limited Mitochondrial Oxidative Stress
por: Ikeda, Masataka, et al.
Publicado: (2015)

Dopamine Therapy and the Regulation of Oxidative Stress and Mitochondrial DNA Copy Number in Patients with Parkinson’s Disease
por: Chen, Shih-Hsuan, et al.
Publicado: (2020)

Analysis of the entire mitochondrial genome reveals Leber’s hereditary optic neuropathy mitochondrial DNA mutations in an Arab cohort with multiple sclerosis
por: Al‐Kafaji, Ghada, et al.
Publicado: (2022)

Mitochondrial DNA haplogroup analysis in Saudi Arab patients with multiple sclerosis
por: Al-Kafaji, Ghada, et al.
Publicado: (2022)

Mitochondrial DNA copy number variation across human cancers
por: Reznik, Ed, et al.
Publicado: (2016)

Global Genetic Determinants of Mitochondrial DNA Copy Number
por: Zhang, Hengshan, et al.
Publicado: (2014)

The regulation of mitochondrial DNA copy number in glioblastoma cells
por: Dickinson, A, et al.
Publicado: (2013)

Mitochondrial DNA copy number and incident atrial fibrillation
por: Zhao, Di, et al.
Publicado: (2020)

Evaluation of mitochondrial DNA copy number estimation techniques
por: Longchamps, Ryan J., et al.
Publicado: (2020)

Association of mitochondrial DNA copy number with cardiometabolic diseases
por: Liu, Xue, et al.
Publicado: (2021)

Increased Mitochondrial DNA Copy Number in Occupations Associated with Low-Dose Benzene Exposure
por: Carugno, Michele, et al.
Publicado: (2011)

Decreased mitochondrial D-loop region methylation mediates an increase in mitochondrial DNA copy number in CADASIL
por: Zhang, Jiewen, et al.
Publicado: (2022)

Simultaneous Quantification of Mitochondrial DNA Damage and Copy Number in Circulating Blood: A Sensitive Approach to Systemic Oxidative Stress
por: Chan, Sam W., et al.
Publicado: (2013)

Alteration of Mitochondrial DNA Copy Number and Increased Expression Levels of Mitochondrial Dynamics-Related Genes in Sjögren’s Syndrome
por: De Benedittis, Giada, et al.
Publicado: (2022)

Maintenance of mitochondrial DNA copy number is essential for osteoclast survival
por: Miyazaki, Tsuyoshi, et al.
Publicado: (2012)

Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice
por: Ylikallio, Emil, et al.
Publicado: (2010)

Mitochondrial DNA Copy Number Is Associated with Breast Cancer Risk
por: Thyagarajan, Bharat, et al.
Publicado: (2013)

Mitochondrial DNA Copy Number in Peripheral Blood and Melanoma Risk
por: Shen, Jie, et al.
Publicado: (2015)

Plasmid-normalized quantification of relative mitochondrial DNA copy number
por: Fazzini, Federica, et al.
Publicado: (2018)

Mitochondrial DNA copy number in human disease: the more the better?
por: Filograna, Roberta, et al.
Publicado: (2020)

Increased mtDNA copy number promotes cancer progression by enhancing mitochondrial oxidative phosphorylation in microsatellite-stable colorectal cancer
por: Sun, Xiacheng, et al.
Publicado: (2018)

Increased copy number of mitochondrial DNA predicts poor prognosis of esophageal squamous cell carcinoma
por: Li, Heng, et al.
Publicado: (2018)

Peripheral Mitochondrial DNA Copy Number is Increased in Korean Attention-Deficit Hyperactivity Disorder Patients
por: Kim, Johanna Inhyang, et al.
Publicado: (2019)

Oryeongsan suppressed high glucose-induced mesangial fibrosis
por: Yoon, Jung Joo, et al.
Publicado: (2015)

Remdesivir increases mtDNA copy number causing mild alterations to oxidative phosphorylation
por: DeFoor, Nicole, et al.
Publicado: (2023)

DNA replication stress restricts ribosomal DNA copy number
por: Salim, Devika, et al.
Publicado: (2017)

Sex and age specific reduction in stress resistance and mitochondrial DNA copy number in Drosophila melanogaster
por: Kristensen, Torsten Nygaard, et al.
Publicado: (2019)

Mycoplasma DnaK increases DNA copy number variants in vivo
por: Benedetti, Francesca, et al.
Publicado: (2023)

Alteration of the copy number and deletion of mitochondrial DNA in human hepatocellular carcinoma
por: Yin, P H, et al.
Publicado: (2004)

Reduced mitochondrial DNA copy number is a biomarker of Parkinson's disease
por: Pyle, Angela, et al.
Publicado: (2016)

Accelerated epigenetic aging and mitochondrial DNA copy number in bipolar disorder
por: Fries, Gabriel R., et al.
Publicado: (2017)

Association of mitochondrial DNA copy number with self-rated health status
por: Takahashi, Paul Y, et al.
Publicado: (2018)

Mitochondrial DNA copy number in affected and unaffected LHON mutation carriers
por: Bianco, Angelica, et al.
Publicado: (2018)

Aberrant telomere length and mitochondrial DNA copy number in suicide completers
por: Otsuka, Ikuo, et al.
Publicado: (2017)

Nucleoside supplementation modulates mitochondrial DNA copy number in the dguok (−/−) zebrafish
por: Munro, Benjamin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_gh5iojrfsgj0jgltgpl7eqlgtc