Cargando…

Protein Kinase A Governs a RhoA-RhoGDI Protrusion-Retraction Pacemaker in Migrating Cells

The cyclical protrusion and retraction of the leading edge is a hallmark of many migrating cells involved in processes such as development, inflammation, and tumorigenesis. The molecular identity of signaling mechanisms that control these cycles has remained unknown. Here, we used live cell imaging...

Descripción completa

Detalles Bibliográficos
Autores principales: Tkachenko, Eugene, Sabouri-Ghomi, Mohsen, Pertz, Olivier, Kim, Chungho, Gutierrez, Edgar, Machacek, Matthias, Groisman, Alex, Danuser, Gaudenz, Ginsberg, Mark H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746034/
https://www.ncbi.nlm.nih.gov/pubmed/21572420
http://dx.doi.org/10.1038/ncb2231