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ST2 deletion enhances innate and acquired immunity to murine mammary carcinoma

ST2 is a member of the IL-1 receptor family and IL-33 was recently identified as its natural ligand. The IL-33/ST2 pathway regulates Th1/Th2 immune responses in autoimmune and inflammatory conditions, but the role of ST2 signaling in tumor growth and metastasis has not been investigated. We aimed to...

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Detalles Bibliográficos
Autores principales: Jovanovic, Ivan, Radosavljevic, Gordana, Mitrovic, Maja, Lisnic Juranic, Vanda, McKenzie, Andrew N J, Arsenijevic, Nebojsa, Jonjic, Stipan, Lukic, Miodrag L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746127/
https://www.ncbi.nlm.nih.gov/pubmed/21484786
http://dx.doi.org/10.1002/eji.201141417