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Multiscale Simulations Reveal Conserved Patterns of Lipid Interactions with Aquaporins

Interactions of membrane proteins with lipid molecules are central to their stability and function. We have used multiscale molecular dynamics simulations to determine the extent to which interactions with lipids are conserved across the aquaporin (Aqp) family of membrane proteins. Simulation-based...

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Detalles Bibliográficos
Autores principales: Stansfeld, Phillip J., Jefferys, Elizabeth E., Sansom, Mark S.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746155/
https://www.ncbi.nlm.nih.gov/pubmed/23602661
http://dx.doi.org/10.1016/j.str.2013.03.005