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Epigallocatechin gallate attenuates L-DOPA-induced apoptosis in rat PC12 cells

In this study, the protective effects of EGCG on L-3,4-dihydroxyphenylalanine (L-DOPA)-induced oxidative cell death in catecholaminergic PC12 cells, the in vitro model of Parkinson's disease, were investigated. Treatment with L-DOPA at concentrations higher than 150 µM caused cytotoxicity in PC...

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Detalles Bibliográficos
Autores principales: Lee, Myung-Yul, Choi, Eun Joo, Lee, Myung-Koo, Lee, Jae-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Nutrition Society and the Korean Society of Community Nutrition 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746157/
https://www.ncbi.nlm.nih.gov/pubmed/23964310
http://dx.doi.org/10.4162/nrp.2013.7.4.249