Neuronal carbonic anhydrase VII provides GABAergic excitatory drive to exacerbate febrile seizures

Brain carbonic anhydrases (CAs) are known to modulate neuronal signalling. Using a novel CA VII (Car7) knockout (KO) mouse as well as a CA II (Car2) KO and a CA II/VII double KO, we show that mature hippocampal pyramidal neurons are endowed with two cytosolic isoforms. CA VII is predominantly expres...

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Detalles Bibliográficos
Autores principales: Ruusuvuori, Eva, Huebner, Antje K, Kirilkin, Ilya, Yukin, Alexey Y, Blaesse, Peter, Helmy, Mohamed, Jung Kang, Hyo, El Muayed, Malek, Christopher Hennings, J, Voipio, Juha, Šestan, Nenad, Hübner, Christian A, Kaila, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746197/
https://www.ncbi.nlm.nih.gov/pubmed/23881097
http://dx.doi.org/10.1038/emboj.2013.160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746197/
https://www.ncbi.nlm.nih.gov/pubmed/23881097
http://dx.doi.org/10.1038/emboj.2013.160

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