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A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal

Embryonic stem (ES) cell self-renewal efficiency is determined by the Nanog protein level. However, the protein partners of Nanog that function to direct self-renewal are unclear. Here, we identify a Nanog interactome of over 130 proteins including transcription factors, chromatin modifying complexe...

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Detalles Bibliográficos
Autores principales: Gagliardi, Alessia, Mullin, Nicholas P, Ying Tan, Zi, Colby, Douglas, Kousa, Anastasia I, Halbritter, Florian, Weiss, Jason T, Felker, Anastasia, Bezstarosti, Karel, Favaro, Rebecca, Demmers, Jeroen, Nicolis, Silvia K, Tomlinson, Simon R, Poot, Raymond A, Chambers, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746198/
https://www.ncbi.nlm.nih.gov/pubmed/23892456
http://dx.doi.org/10.1038/emboj.2013.161