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Two mixed-NH(3)/amine platinum (II) anticancer complexes featuring a dichloroacetate moiety in the leaving group

Two mixed-NH(3)/amine platinum (II) complexes of 3-dichoroacetoxylcyclobutane-1, 1-dicarboxylate have been prepared in the present study and characterized by elemental analysis and IR, HPLC-MS and (1)H, (13)C-NMR. The complexes exist in equilibrium between two position isomeric forms and undergo hyd...

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Detalles Bibliográficos
Autores principales: Liu, Weiping, Su, Jia, Jiang, Jing, Li, Xingyao, Ye, Qingsong, Zhou, Hongyu, Chen, Jialin, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746205/
https://www.ncbi.nlm.nih.gov/pubmed/23955304
http://dx.doi.org/10.1038/srep02464