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Effects of structural analogues of apelin-12 in acute myocardial infarction in rats

OBJECTIVE: To examine cardioprotective effects of Ρ-terminal fragment of adipokine apelin-12 (A12), its novel structural analogue [MeArg(1), NLe(10)]-A12 (I), and [d-Ala(12)]-A12 (II), a putative antagonist of APJ receptor, employing in vivo model of ischemia/reperfusion (I/R) injury. MATERIALS AND...

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Detalles Bibliográficos
Autores principales: Pisarenko, Oleg I., Serebryakova, Larisa I., Studneva, Irina M., Pelogeykina, Yulia A., Tskitishvili, Olga V., Bespalova, Zhanna D., Sidorova, Maria V., Az’muko, Andrei A., Khatri, Denis N., Pal’keeva, Maria E., Molokoedov, Alexander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746303/
https://www.ncbi.nlm.nih.gov/pubmed/23960425
http://dx.doi.org/10.4103/0976-500X.114600