Blood levels of histone-complexed DNA fragments are associated with coagulopathy, inflammation and endothelial damage early after trauma

BACKGROUND: Tissue injury increases blood levels of extracellular histones and nucleic acids, and these may influence hemostasis, promote inflammation and damage the endothelium. Trauma-induced coagulopathy (TIC) may result from an endogenous response to the injury that involves the neurohumoral, in...

Descripción completa

Detalles Bibliográficos
Autores principales: Johansson, Pär I, Windeløv, Nis A, Rasmussen, Lars S, Sørensen, Anne Marie, Ostrowski, Sisse R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746437/
https://www.ncbi.nlm.nih.gov/pubmed/23960372
http://dx.doi.org/10.4103/0974-2700.115327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746437/
https://www.ncbi.nlm.nih.gov/pubmed/23960372
http://dx.doi.org/10.4103/0974-2700.115327

Ejemplares similares